The advent of generic versions of nine branded agents will significantly constrain growth in the hospital-acquired infections (HAI) drug market through 2019 in the USA, France, Germany, Italy, Spain, the UK and Japan, according to research and advisory firm Decision Resources.
These nine agents - piperacillin/tazobactam (Pfizer's Zosyn/Tazocin, generics), linezolid (Pfizer's Zyvox), daptomycin (Cubist/Novartis' Cubicin), imipenem/cilastatin (Merck & Co's Primaxin), meropenem (AstraZeneca/Cubist's Merrem), ertapenem (Merck's Invanz), doripenem (Shionogi's Finibax/Ortho-McNeil's Doribax), levofloxacin (Johnson & Johnson's Levaquin, Sanofi-Aventis's Tavanic, Daiichi Sankyo's Cravit) and moxifloxacin (Bayer/Merck's Avelox) - garnered 65% of total market sales in the HAI drug market in 2009. Owing to generic erosion, combined sales of these agents will be reduced to 40% of the overall market in 2019.
Uptake of Vibativ, Teflaro and torezolid will help offset downturn
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