Fulcrum failure sends shares 61% downwards
Thursday was a wretched day for Fulcrum Therapeutics, (Nasdaq: FULC), a US biopharma company focused on developing small molecules to improve the lives of patients with genetically defined rare diseases.
Shares in the Boston firm closed 61% lower after it was announced that its Phase III REACH trial evaluating losmapimod in patients with facioscapulohumeral muscular dystrophy (FSHD), did not achieve its primary endpoint of change from baseline in relative surface area (RSA) compared to placebo, after 48 weeks.
Secondary endpoints did not achieve nominal statistical significance, either.
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