Four oral GLP-1R drugs in Phase III obesity trials as race hots up

2 December 2024

GLP-1 receptor (GLP-1R) products have gained immense popularity in recent years, and four are currently approved in major markets to treat obesity - all of which are injectables.

This leaves a gap in the obesity market for an oral GLP-1R product, with an overview of the field from GlobalData finding that 63 drugs are in active development, with four Phase III products racing to earn the inaugural approval in this untapped market.

The background to this is the obesity epidemic. By 2030, half of all US adults are predicted to be obese, according to the New England Journal of Medicine. 

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