ESMO 2024: Merck & Co keeps Keytruda data coming

16 September 2024

As ever, US pharma giant Merck & Co (NYSE: MRK) has been sharing plenty of data on its blockbuster anti-PD-1 therapy Keytruda (pembrolizumab) at this year’s meeting of the European Society for Medical Oncology (ESMO).

One of the most important has been the first-time presentation of overall survival (OS) results from the Phase III KEYNOTE-522 trial evaluating Keytruda in combination with chemotherapy as neoadjuvant treatment and then continuing as a single agent after surgery for the treatment of patients with high-risk early-stage triple-negative breast cancer (TNBC).

After a median follow-up of 75.1 months, the Keytruda regimen significantly improved OS, a key secondary endpoint, reducing the risk of death by 34% in patients with high-risk early-stage TNBC compared to the chemotherapy-placebo regimen

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