ESMO 2024: Encouraging mid-stage results on BioNTech asset

17 September 2024

A cancer drug in-licensed by German biotech major BioNTech (Nasdaq: BNTX) from China-based Biotheus could be a good one, if mid-stage results shared at the European Society for Medical Oncology (ESMO) are anything to go by.

PM8002/BNT327 is a bispecific antibody targeting PD-L1 and VEGF-A. BioNTech agreed to pay up to $1 billion to develop the drug in an agreement with Biotheus signed in November last year.

Results have been presented at ESMO from a single-arm Phase II safety and efficacy study of PM8002/BNT327 in combination with chemotherapy in patients with EGFR-mutated non-small cell lung cancer (NSCLC).

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