New Jersey, USA-based Enzon Pharmaceuticals has received European Orphan Drug designation for its Oncaspar-IV (EZN-2285), a next-generation PEG- enhanced version of L-asparaginase. The firm says the product, which is a new version of its Oncaspar, utilizes an efficient modern process for the manufacture of L-asparaginase and an improved PEG linker to enhance stability. The original Oncaspar is used in combination with other chemotherapeutics to treat acute lymphoblastic leukemia. The firm says Oncaspar-IV is designed to enhance the pharmaceutical properties of the original US approved drug.
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