German drugmaker Dr Falk Pharma GmbH today announced completion of the acquisition of Kynos Therapeutics, a clinical stage biopharmaceutical company focusing on the development of novel KMO inhibitors for acute and chronic inflammatory diseases. Financial terms of the transaction are not disclosed.
The company was spun out of the University of Edinburgh by co-founders Professors Damian Mole and Scott Webster, together with founding investor Epidarex Capital, a leading early-stage transatlantic venture fund. The company has been backed by investment from Epidarex Capital, IP Group, and Scottish Enterprise and led by CEO Jonathan Savidge since 2022.
Since its foundation, Kynos Therapeutics has progressed development of its lead molecule, KNS366, a highly potent and selective first-in-class inhibitor of the enzyme kynurenine 3-monooxygenase (KMO), through a Phase I trial. KNS366 was shown to be safe and well-tolerated and led to a dose-dependent inhibition of the enzyme KMO and modulation of its downstream metabolites.
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