Destiny Pharma’s XF-73 nasal gel cuts need for post-cardiac surgical antibiotics
UK-based biotech Destiny Pharma (AIM: DEST) saw its shares fall almost 15% to 4.00 pence this morning, despite announcing positive trial results.
Destiny revealed new clinical data from its Phase IIb clinical trial on XF-73 in cardiac surgery patients. Further planned data analysis of a secondary endpoint within the clinical trial investigated the use by physicians of post-surgical systemic antibiotics prescribed >48 hours after surgery.
Significantly fewer patients in the XF-73 treatment arm received post-operative anti-staphylococcal antibiotics: 46.5% (20 of a total population of 43), compared to 70% (28 of a total population of 40) in the placebo group, p=0.045, which suggests that antibiotics may have been prescribed as an early intervention in more patients in the placebo arm.
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