CRISPR gene editing company cuts program and jobs

10 January 2025

Intellia Therapeutics (Nasdaq: NTLA), a US gene editing company developing CRISPR-based therapies, announced late Thursday its strategic priorities and key anticipated 2025 milestones.

There will be a pipeline prioritization intended to focus resources on high value programs, these being NTLA-2002 for hereditary angioedema (HAE) and nexiguran ziclumeran (nex-z) for transthyretin (ATTR) amyloidosis, to ensure efficient execution, achieve near-term clinical milestones and prepare Intellia for commercial launch. 

As part of this prioritization, the company has discontinued development of NTLA-3001 for the treatment of alpha-1 antitrypsin deficiency-associated lung disease and select research-stage programs. 

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