The global central nervous system (CNS) market is projected grow to over $80 billion in sales in 2025 for the first time since 2013, making a significant resurgence after a decade of stagnation.
This revival positions CNS as the fifth-fastest growing therapy area in 2025, driven by strong multiple sclerosis (MS) drug sales and renewed psychiatric drug innovation, according to pharma analytics company GlobalData.
The revival of CNS drug development is being fueled by advancements in neuroimmunology and neurodegeneration, moving beyond conventional dopamine and serotonin pathways. Leading the shift are from Swiss pharma giants Roche (ROG: SIX) with Ocrevus (ocrelizumab) and Novartis (NOVN: VX) with Kesimpta (ofatumumab) - two anti-CD20 monoclonal antibodies - expected to dominate the market. Ocrevus alone is forecasted to generate $8.1 billion in sales, accounting for nearly 10% of the total CNS revenue.
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