Japanese drugmaker Chugai (TYO: 4519), which is majority-owned by Swiss drug major Roche (ROG: SIX), has gained marketing rights to palonosetron in the UK and NEPA in the UK and Ireland from privately-held Swiss cancer specialists Helsinn Group.
The two companies are partnering on NEPA, an investigational oral fixed-dose combination of netupitant and palonosetron being evaluated for the prevention of chemotherapy-induced nausea and vomiting. Chugai has additionally been granted exclusive rights to market the palonosetron monotherapy, Aloxi (palonosetron HCI), in the UK from January next year.
NEPA is currently in the registration phase in the USA and Europe, and one of its components is palonosetron, the market-leading treatment for chemotherapy-induced nausea and vomiting. Palonosetron achieved worldwide sales in the region of $625 million in 2013, and is available in over 65 countries worldwide under the brand names of Aloxi, Onicit and Paloxi.
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