China greenlight for Innovent’s Dupert

22 August 2024

China's National Medical Products Administration (NMPA) has approved domestic biopharma firm Innovent Biologics’ (HKEX: 01801) Dupert(fulzerasib) for the treatment of adult patients with advanced non-small cell lung cancer (NSCLC) harboring KRAS G12C mutation who have received at least one systemic therapy.

As China's first approved KRAS G12C inhibitor, Dupert is Innovent's eleventh product in its commercial portfolio and is anticipated to soon benefit more lung cancer patients with the KRAS G12C mutation.

In September 2021, Innovent and Shanghai-based GenFleet Therapeutics entered into an exclusive license agreement for the development and commercialization of fulzerasib in China(including mainland China, Hong Kong, Macau and Taiwan).

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