Boehringer’s zongertinib shows encouraging profile in NSCLC

10 September 2024

German family-owned pharma major Boehringer Ingelheim has reported positive results from a Phase Ib primary analysis of Cohort 1 of the Beamion LUNG-1 trial evaluating zongertinib (BI 1810631) in pre-treated patients with advanced non-small cell lung cancer (NSCLC) with activating HER2 mutations.

Zongertinib demonstrated a meaningful objective response rate and was generally well tolerated in the Cohort 1 setting. The results were presented in a Presidential Symposium at the IASLC 2024 World Conference on Lung Cancer (WCLC) and are included in the official 2024 WCLC Press Program.

Boehringer has previously indicated it is looking to bring that therapy to market in the first half of 2025. Armed with an existing infrastructure for its marketed EGFR-mutated NSCLC med Giotrif (afatinib), Boehringer is already busy building out its commercial resources.

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