German family-owned pharma major Boehringer Ingelheim today said it is taking a significant step in expanding its oncology pipeline of cancer cell-directed and immuno-oncology offering.
Boehringer revealed it is adding an innovative pre-clinical program with the acquisition of Nerio Therapeutics for a total of up to $1.3 billion. Boehringer did not disclose how much it was paying upfront, but said it aims to develop this program as a potential key centerpiece component for its immuno-oncology portfolio to achieve its aim of improving cancer patient outcomes.
California, USA-based Nerio’s small molecules inhibit the protein tyrosine phosphatases N1 and N2 (PTPN1 and PTPN2), which act as immune checkpoints. Through this mechanism, PTPN1/2 inhibition can activate the immune system to fight cancer cells.
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