BMS returns AGEN1777 rights to Agenus

5 August 2024

US immuno-oncology (I-O) focussed biotech Agenus (Nasdaq: AGEN) has revealed via a Securities and Exchange Commission (SEC) filing that US pharma major Bristol Myers Squibb (NYSE: BMS) was pulling out of a licensing deal.

Agenus said that, on July 30, 2024, it received notice from BMS that, as part of a broader strategic realignment of its development pipeline which involves other licensed products, it is returning rights to Agenus’ proprietary bispecific antibody program, AGEN1777, that blocks TIGIT, back to Agenus and voluntarily terminating the BMS license agreement, effective as of January 26, 2025.

When AGEN1777 was initially licensed to BMS, it had no clinical data. Since then, significant safety data has been generated in early clinical trials with indications of clinical activity. Agenus intend to explore further development and/or relicensing of this molecule, including potential combinations with our portfolio of synergistic immuno-oncology agents.

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