BMS data support potential for Sotyktu to impact joint and skin symptoms

10 March 2025

US pharma major Bristol Myers Squibb (NYSE: BMY) has announced positive data from the pivotal Phase III POETYK PsA-2 trial evaluating the efficacy and safety of Sotyktu (deucravacitinib) in adults with active psoriatic arthritis (PsA).

This study met its primary endpoint, with a significantly greater proportion of Sotyktu-treated patients achieving at least a 20% improvement in signs and symptoms of disease compared with placebo at week 16.

Sotyktu’s overall safety profile through 16 weeks of treatment was consistent with that established in a Phase II PsA trial and Phase III moderate-to-severe plaque psoriasis studies.

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