Zymeworks in deal to advance antibody discovery work

12 August 2016

Privately-held Canadian biotech firm Zymeworks has joined forces with Innovative Targeting Solutions (ITS) to strengthen its in-house antibody discovery capabilities.

Under the terms of the collaboration, Zymeworks, which develops protein therapeutics for the treatment of cancer as well as for autoimmune and inflammatory diseases, will in-license and integrate ITS’ proprietary HuTARG platform to help identify and develop therapeutics directed towards challenging disease targets.

This is a protein engineering platform which has been billed as representing a disruptive technology in the field. It is the first fully mammalian technology that generates antibody diversity in vitro via RAG1/RAG2 mediated V(D)J recombination, allowing for the generation and affinity maturation of highly potent protein-based biologics.

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