Xyphos Biosciences collaborates on CAR-T cells for cancer treatment

18 October 2018

The Parker Institute for Cancer Immunotherapy and Xyphos Biosciences today announced a collaboration to create universal CAR-T therapies to treat multiple cancer types using the company's 'convertibleCAR' platform.

Xyphos was created last November as a spin-out from AvidBiotics, a privately held US biotechnology company.

Using this type of cell therapy, researchers endeavor to program a patient's own immune cells to attack tumor cells with greater specificity, and potentially lower toxicity, when directed to tumor antigens with separate targeting antibodies. Unlike the first generation of approved cell therapies, this technology aims to allow more controlled antigen recognition for greater responsiveness to the tumor environment.

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