Hong Kong-listed WuXi Biologics (2269.HK) and NBE-Therapeutics, a privately-owned Swiss biotech have announced a comprehensive development and manufacturing partnership for NBE's first ADC lead product NBE-002 (anti-ROR1).
NBE-002 is a best-in-class immune-stimulatory ADC (iADC) treatment against the ROR1 cancer target and is planned to enter into clinical trials in mid 2020 in triple negative breast cancer and other indications.
NBE-Therapeutics develops next-generation iADC products with the aim to improve the outcome for cancer patients, as it continues to develop iADCs based on its proprietary technology platforms. With its proprietary SMAC-Technology to generate site-specifically conjugated ADCs and its proprietary highly-potent anthracycline toxin platform, NBE has the ability to develop highly targeted treatments with long-lasting anti-tumor immunity.
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