Vertex Pharmaceuticals (Nasdaq: VRTX) was up 19% in pre-market trading on Wednesday at $106.85 on the back of results from two Phase III studies in cystic fibrosis (CF).
The US biotech firm announced that the studies of the tezacaftor (VX-661)/ivacaftor combination treatment met their primary endpoints by showing statistically significant improvements in lung function in patients with the disease who have certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
"This combination may provide a promising new option for treating the underlying cause of CF in the future"
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