Vertex leaps on positive Ph III results with lumacaftor

24 June 2014

US biotech firm Vertex Pharmaceuticals (Nasdaq: VRTX) saw its share price rocket nearly 52% to $101.20 in extending trading yesterday after the company released new research data with its lumacaftor.

The company announced results from two Phase III studies of lumacaftor in combination with ivacaftor (Vertex’ already marketed Kalydeco brand) that showed statistically significant improvements in lung function (percent predicted forced expiratory volume in one second, or ppFEV1) in people ages 12 and older with cystic fibrosis (CF) who have two copies (homozygous) of the F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

Study details

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