Vertex and Moderna collaborate on mRNA Therapeutics for cystic fibrosis

7 July 2016

Vertex Pharmaceuticals (Nasdaq: VRTX) and privately-held US biotech firm Moderna Therapeutics have entered into an exclusive research collaboration and licensing agreement aimed at the discovery and development of messenger Ribonucleic Acid (mRNA) Therapeutics for the treatment of cystic fibrosis (CF).

The three-year collaboration will focus on the use of mRNA therapies to treat the underlying cause of CF by enabling cells in the lungs to produce functional copies of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, which is known to be defective in people with CF. Through the collaboration, the companies will explore the potential utilization of pulmonary mRNA delivery.

Deal potentially worth up to $315 million

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