Verona Pharma hints at COPD breakthrough with RPL554
UK biotech Verona Pharma (LSE: VRP) has announced positive headline data from a Phase IIa study on the bronchodilator effect of nebulized RPL554, administered on top of salbutamol and ipratropium bromide, for chronic obstructive pulmonary disease (COPD).
The company believes this could address a multi-million dollar market in providing an answer for patients with COPD, the name for a collection lung conditions including chronic bronchitis, emphysema and chronic obstructive airways disease.
RPL554 is a new inhaled dual PDE3/PDE4 inhibitor with both bronchodilator and anti-inflammatory properties in the same molecule. It is currently in development as a nebulized treatment for acute exacerbations in COPD patients in a hospital or for maintenance treatment in a home-care setting.
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