Vaxxinity touts cost-effective vaccine for mix and match boosting

2 December 2022

US immunotherapeutic vaccines company Vaxxinity (Nasdaq: VAXX) has announced positive Phase III topline data for its COVID-19 booster vaccine, UB-612.

In the trial, the multitope subunit protein/peptide-based vaccine candidate was delivered as a heterologous booster in three separate substudies in populations previously vaccinated with Pfizer (NYSE: PFE) and BioNTech’s (Nasdaq: BNTX) Comirnaty, AstraZeneca’s Vaxzevria, or Sinopharm’s BIBP.

UB-612 elicited superior neutralizing antibody titers and seroconversion rates against both Wuhan and Omicron BA.5 variants compared to AstraZeneca’s adenovirus vector vaccine and Sinopharm’s inactivated virus jab.

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