UK's NICE recommends Stelara for psoriatic arthritis

12 March 2015

Medicines cost watchdog for England, the National Institute for Health and Clinical Excellence (NICE), has recommended Johnson & Johnson (NYSE: JNJ) subsidiary Janssen’s Stelara (ustekinumab) in its Final Appraisal Determination (FAD) as a treatment option for patients with active psoriatic arthritis, when the response to previous non-biological disease-modifying anti-rheumatic drug (DMARD) therapy has been inadequate.

According to the FAD, ustekinumab is recommended as an option, alone or in combination with methotrexate, for treating active psoriatic arthritis in adults only when:

treatment with tumor necrosis factor (TNF) alpha inhibitors is contraindicated but would otherwise be considered; or
the person has had treatment with one or more TNF-alpha inhibitors.

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