Trial shows viability of Sirnaomics' siRNA therapeutic

30 August 2022

Sino-American RNAi therapeutics company Sirnaomics (2257: HK) has announced that the cohort receiving the 180μg dose in its Phase II trial of STP705 for cutaneous basal cell carcinoma (BCC) achieved a 100% complete response (CR), indicating the promising viability of the treatment.

STP705 is a small interfering RNA (siRNA) therapeutic that is composed of two siRNA oligonucleotides, targeting the expression of TGF-β1 and COX-2 mRNA, respectively.

"Sirnaomics is spearheading the development of the novel polypeptide-based siRNA therapeutics for various types of cancers"

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