Trial doubts take the shine off results on Roche's tiragolumab

19 January 2024

Swiss pharma giant Roche (ROG: SIX) presented positive Phase III data on its anti-TIGIT immunotherapy tiragolumab in esophageal cancer this week.

The findings from the SKYSCRAPER-08 study, which were presented in an abstract ahead of the 2024 ASCO Gastrointestinal Cancers Symposium, follow two prior late-stage setbacks for the drug.

But, due to the use of a comparator that is no longer considered the standard of care, there are questions about how important the data are.

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