Tokai shares decimated by halting of Phase III galeterone trial in prostate cancer

27 July 2016
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USA-based biotech Tokai Pharmaceuticals (Nasdaq: TKAI) suffered a seismic 79% drop in its share price on Tuesday after the company announced the discontinuation of the ARMOR3-SV trial.

This is the pivotal Phase III study comparing galeterone, Tokai’s lead drug candidate, to enzalutamide in the treatment-naïve metastatic castration-resistant prostate cancer (mCRPC) patients whose prostate tumors express AR-V7.

The decision to halt the trial follows the recommendation made on Monday by the study’s independent Data Monitoring Committee (DMC).

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