Tiragolumab takes another hit with Phase III miss

26 November 2024

The Phase III SKYSCRAPER-01 trial has missed its primary endpoint, Swiss cancer giant Roche (ROG: SIX) has reported.

The study is testing tiragolumab, combined with Tecentriq (atezolizumab), in certain people with advanced or metastatic non-small cell lung cancer (NSCLC).

Compared with Tecentriq monotherapy, the combination did not demonstrate a statistically-significant improvement in overall survival (OS). Roche said it would keep trialing the therapy in other tumor types, with additional data expected next year.

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