The week in pharma: action, reaction and insight – week to October 28, 2022

30 October 2022

By Barbara Obstoj-Cardwell. Editor

Among significant research news last week, Swiss pharma giant Novartis announced Phase III results for its investigational drug iptacopan, demonstrating superiority to AstraZeneca’s blockbuster franchise – Solaris and Ultomiris - in the treatment of hemoglobinuria (PNH). Mirum Pharmaceuticals released new Phase III data on Livmarli, a proposed treatment for the rare pediatric disease familial intrahepatic cholestasis (PFIC). And UK pharma major GSK last Thursday revealed it is discontinuing development of the investigational drug otilimab in rheumatoid arthritis. Also of note, Johnson & Johnson’s Janssen unit last Tuesday received a second approval for its multiple myeloma drug Tecvayli, this time from the US Food and Drug Administration (FDA).

Novartis’ Solaris challenger clears the first hurdle

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