The week in pharma: action, reaction and insight – week to February 17, 2023

19 February 2023
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By Barbara Obstoj-Cardwell. Editor

Research news featured last week, first with US pharma giant Bristol Myers Squibb and 2seventy bio presenting Phase III results for their CAR-T cell therapy Abecma (ide-cel) in multiple sclerosis. Also, G1 Therapeutics announced it was terminating a trial of its Cosela (trilaciclib) in colorectal cancer. Additionally, Pfizer released new Phase III data on its Talzenna in combination with Xtandi that missed one of its objectives. On the deal-making front, US drug developer Cullinan Oncology entered into a collaboration with China-based Harbour BioMed for the development of a potential cancer treatment, HBM7008/CLN-418, and USA-based Arrowhead Pharma revealed that Johnson & Johnson subsidiary Janssen has pulled out of a 2018 collaboration on the development of non-alcoholic steatohepatitis (NASH) candidate ARO-PNPLA3, formerly JNJ-75220795.

Positives and uncertainties in KarMMA-3 trial on ide-cel in earlier MM

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