Teijin and Amgen join forces on autoimmune disease research

31 July 2013

Japan’s Teijin Pharma, the core company of the Teijin Group’s (TSE: 3401) health care business, has entered into a collaborative agreement with Amgen (Nasdaq: AMGN), the world’s largest independent biotech firm, to discover, develop and commercialize small molecule drugs that target RORγ.

The agreement grants Amgen an option to obtain a worldwide (ex-Japan) exclusive license to compounds discovered in the joint research collaboration, while Teijin Pharma will hold exclusive rights in Japan.

Teijin and Amgen will work together to identify candidates that modulate the activity of RORγ, an emerging and promising target for autoimmune disease drug development. RORγ is a key driver of differentiation and regulation of Th17 cells, which play a pivotal role in inflammation and are broadly implicated in autoimmune diseases.

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