Takeda using 'every possible channel' to deliver on Adcetris potential, says Thanos Zomas

22 July 2019

As the global medical lead of the Adcetris (brentuximab vedotin) program for Japanese pharma major Takeda (TYO: 4502), Thanos Zomas’ job was made easier by Phase III trial results that he describes as “almost unprecedented.”

The randomized ALCANZA study, initially developed to compare Adcetris to physician’s choice in CD30+ cutaneous T-cell lymphoma (CTCL), delivered highly statistically-significant improvements in terms of sustainability and quality of life.

Results showing a highly statistically-significant improvement in the rate of objective response lasting at least four months were presented almost three years ago, and it was around that time and because of such promising research that Dr Zomas left his role in academia to join Takeda, which partners with Seattle Genetics (Nasdaq: SGEN) on Adcetris.

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