Takeda to commercialize and develop cabozantinib in Japan

31 January 2017

Takeda Pharmaceutical (TYO: 4502) has entered into an exclusive licensing agreement for the commercialization and further clinical development in Japan of cabozantinib, USA-based biotech firm Exelixis’ (Nasdaq: EXEL) lead oncology medicine.

With the signing of the agreement, Takeda, Japan's largest drugmaker, gains exclusive commercial rights for all potential future cabozantinib indications in Japan, including advanced renal cell carcinoma (RCC), for which cabozantinib is marketed in the USA and European Union as Cabometyx tablets. The two companies will collaborate on the future clinical development of cabozantinib in Japan.

Under the terms of the accord, Exelixis will receive a $50 million upfront payment, and is eligible to receive development, regulatory, and first-sales milestones of $95 million for the first three planned indications. In addition, Exelixis will be eligible to receive royalties on sales by Takeda.

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