Takeda's Exkivity needs more data to defeat domestic rivals in China, says analyst

27 January 2023

Exkivity (mobocertinib) is the first targeted therapy to be approved for locally-advanced or metastatic epidermal growth factor receptor (EGFR) exon 20 insertions (exon20ins)-positive non-small cell lung cancer (NSCLC) in China.

The drug from Japanese pharma major Takeda (TYO: 4502) has been approved under the National Medical Products Administration’s Breakthrough Therapy program for second-line treatment.

However, there still exists room for improvement to treat this subset of patients, given the treatment outcomes and safety of the molecule in the pivotal Phase II trial, according to GlobalData.

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