Takeda pulls out of option deal on MacroGenics' MGD010

13 September 2016
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USA-based MacroGenics (Nasdaq: MGNX) has announced that Takeda Pharmaceutical (TYO; 4502) will drop its license and option agreement for MGD010, which has been under development for the treatment of autoimmune diseases.

MacroGenics has regained the worldwide rights to MGD010, a bispecific molecule targeting CD32B and CD79B. The decision by Takeda, Japan’s largest drugmaker, comes earlier than the predefined expiration of its option exercise period and follows Takeda’s recently announced therapeutic area re-prioritization.

Takeda’s decision was not based on the ongoing Phase I study with MGD010. MacroGenics plans to continue to advance the development of this product candidate based on the positive study results reported to date.

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