Takeda and Wave agree $230 million-plus collaboration in CNS disorders

21 February 2018

East Coast, USA-based Wave Life Sciences (Nasdaq: WVE) has landed a near quarter billion dollar deal with Japan’s Takeda Pharmaceutical (TYO: 4502) to bring forward nucleic acid therapies for central nervous system disorders.

Takeda will pay $110 million upfront and purchase $60 million of Wave’s shares. The firm will also pay a minimum of $60 million to fund Wave’s research over a four-year period.

In return, the Tokyo-based drugmaker will receive the option to co-develop and co-commercialize programs in Huntington’s disease (HD), amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and spinocerebellar ataxia type 3 (SCA3).

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