Synergy shares tumble despite positive plecanatide results

12 December 2016

USA-based biopharma group Synergy Pharmaceuticals (Nasdaq: SGYP) has announced positive top-line results from the first of two pivotal Phase III trials of plecanatide in irritable bowel syndrome with constipation (IBS-C).

Friday’s results caused an immediate 12% jump in the company’s share price on Friday morning to $6.24, but this rise has been more than cancelled out since, a drop attributed by Fox News to investor uncertainty.

The trial evaluated the efficacy and safety of plecanatide, an investigational once-daily orally-administered compound, in 1,135 adult patients with IBS-C.

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