CGT Catapult, part of a UK government-led industry-boosting initiative, has entered into a collaboration with Swedish neurological specialist CombiGene, related to epilepsy candidate CG01.
The project is aimed at developing a novel manufacturing process for the gene therapy, allowing CombiGene to progress to commercial GMP production and thereafter clinical trials.
The company has developed a platform which uses gene therapy vectors to deliver a combination of neuropeptide y (NPY) and NPY receptors into brain cells. This has been shown in preclinical studies to inhibit epileptic seizures.
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