US-based biotech company Regeneron (Nasdaq: REGN) has said its Phase III trials of Eylea (aflibercept) injection for the treatment of diabetic muscular edema has shown sustained improvement from baseline in best corrected visual acuity at week 100 (two years), compared to laser photocoagulation. Eylea is under development with German pharma major Bayer (BAYN: DE).
The trial is testing the Eylea 2mg dosed monthly and Eylea 2mg dosed every two months after five initial monthly injections, in a randomized allocation involving both Eylea doses and the comparator treatment of laser photocoagulation.
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