US firm Sorrento Therapeutics (Nasdaq: SRNE) has set up a joint venture with NantBioScience, a majority-owned subsidiary of privately-held NantWorks, to focus on the development of 'first-in-class' small molecules against targets that have eluded the pharmaceutical industry to date and which may address important drivers of cancer growth including cancer stem cells.
Sorrento, a clinical stage oncology company, will contribute key small molecule programs (lead inhibitors of the proto-oncogenes c-Myc, and the master metabolism regulator HIF-1 alpha, and an inducer of the tumor suppressor cytokine TRAIL) to the joint venture which will be 60% owned by NantBioScience and 40% owned by Sorrento, and funded accordingly.
Adds to earlier collaborations
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