Shattuck Labs cuts workforce and shifts focus

2 October 2024

American biotech Shattuck Labs has announced plans to reduce its workforce by approximately 40%, bringing its employee count below 50.

The news comes as the company said it was also discontinuing its clinical program for SL-172154 and will now concentrate its resources on SL-325, which it believes could become a first-in-class DR3 antagonist antibody.

The decision follows results from Phase I trials where SL-172154 did not show significant improvements in median overall survival for patients with TP53-mutant acute myeloid leukemia and high-risk myelodysplastic syndromes.

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