Santhera snaps up CF drug in all-Swiss deal

15 February 2018

Santhera Pharmaceuticals (SIX: SANN) has signed a deal to give it exclusive worldwide rights to a drug developed by fellow Swiss firm Polyphor with financial support from the USA’s Cystic Fibrosis Foundation Therapeutics.

Currently known as POL6014, the drug is a clinical-stage selective inhibitor of human neutrophil elastase with the potential to treat cystic fibrosis (CF) and other neutrophilic pulmonary diseases such as non-cystic fibrosis bronchiectasis (NCFB), alpha-1 antitrypsin deficiency (AATD) and primary ciliary dyskinesia (PCD).

Santhera will pay 6.5 million Swiss francs ($7.02 million) upfront and additional cash payments of up to 121 million francs contingent to future development, regulatory and particularly sales milestones.

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