Sanofi scraps venglustat in ADPKD
Shares in French drugmaker Sanofi (Euronext: SAN) looked set to close 1% lower on Tuesday after announcing an update on the venglustat clinical program.
The company said that a pivotal Phase II/III study of venglustat in autosomal dominant polycystic kidney disease (ADPKD) had not met futility criteria, and Sanofi has therefore halted the clinical program in ADPKD.
The STAGED-PKD study was stopped for futility following an independent analysis of the annualized rate of change in total kidney volume (TKV) in patients receiving venglustat compared to placebo.
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