Sanofi's Sarclisa data to form basis of future filing

7 December 2023

French pharma major Sanofi (Euronext: SAN) has provided an update from its Phase III IMROZ trial.

The study of the investigational use of Sarclisa (isatuximab) alongside standard-of-care bortezomib, lenalidomide and dexamethasone (VRd) met its primary endpoint at a planned interim analysis for efficacy, demonstrating statistically-significant improvement in progression-free survival (PFS) compared with VRd alone in transplant-ineligible patients with newly-diagnosed multiple myeloma (MM).

It is the first global Phase III study to report positive results with an anti-CD38 therapy in combination with VRd in transplant-ineligible patients, reinforcing the potential for Sarclisa as a best-in-class medicine.

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