Privately-held Singapore-headquartered biotech firm S*BIO Pte has announced the restructuring of its collaboration and option agreement with US drug developer Onyx Pharmaceuticals (Nasdaq: ONXX), which was entered into in January 2009.
As a result, S*BIO has regained North American and European rights to its novel JAK2 inhibitors, SB1518 and SB1578, from Onyx. Following a successful and productive partnership with Onyx, S*BIO says it will now be in a position to drive the development of its lead JAK2 program independently. S*BIO licensed the two products to Onyx in a deal that was worth a potential $550 million to the Singapore company, $25 million of which was paid upfront (The Pharma Letter January 12, 2009).
SB1518 promising in Phase II trials for MF
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