Rybrevant combo gains EU nod in first-line lung cancer

30 December 2024

Johnson & Johnson (NYSE: JNJ) has secured European approval for Rybrevant (amivantamab) in combination with Lazcluze (lazertinib), as a first-line treatment for certain patients with non-small cell lung cancer (NSCLC).

The nod follows US approval earlier in the year, and is based on statistically-significant data from the Phase III MARIPOSA study.

The trial showed that the multitargeted, chemo-free combination reduced the risk of disease progression or death by 30% compared to Tagrisso (osimertinib) monotherapy.

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