Clovis continues fight for share of PARP blocker market

4 October 2022

Positive top-line data for Clovis Oncology’s (Nasdaq: CLVS) PARP blocker Rubraca (rucaparib) could help the firm compete with more successful options in this class, but the benefit appears limited.

The Colorado, USA-based company revealed the TRITON3 trial, the confirmatory study for Rubraca’s current US accelerated approval in metastatic castration-resistant prostate cancer, met its primary efficacy endpoint.

The trial compares the impact of Rubraca monotherapy with doctor’s choice of therapy, either docetaxel, abiraterone acetate, or enzalutamide.

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