Roquefort updates on development of new novel siRNA therapeutics

7 August 2023
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Shares of UK-based biotech Roquefort Therapeutics (LSE: ROQ) were up 9.3% at 8.88 pence by early afternoon, as it announced the successful development of new siRNA sequences and new patent filing for its family of novel anti-cancer siRNA therapeutics.

Following the company's acquisition of Oncogeni in September 2022 for around $4.9 million, where Roquefort Therapeutics acquired a portfolio of pioneering pre-clinical siRNA anti-cancer medicines with significant in vivo efficacy, Roquefort’s drug discovery team, led by vice president of drug discovery, Professor Graham Robertson, has recently developed four additional siRNA sequences to complement the existing siRNA portfolio. The new siRNA sequences expand the company's portfolio of siRNA medicines that attack the targets STAT-6 (Signal Transducer and Activator of Transcription) and its SH2 (Src-homology-2) domain.

The company has recently completed a new patent filing to strengthen its siRNA patent position to protect both the composition of matter and methods of use.

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