US immuno-oncology specialist NewLink Genetics (Nasdaq: NLNK) lost 41% of its value on Thursday after Swiss pharma giant Roche’s (ROG: SIX) Genentech unit handed back the rights to the cancer candidate GDC-0919 (navoximod).
GDC-0919 is an indoleamine-pyrrole 2,3-dioxygenase (IDO) inhibitor that was part of a solid tumor therapy collaboration between the companies signed in 2014, and as part of which Genentech paid NewLink $150 million upfront.
NewLink’s research collaboration with Genentech for the discovery of next generation IDO/TDO (tryptophan 2,3-dioxygenase) inhibitors continues.
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